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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP9B
All Species:
36.06
Human Site:
S453
Identified Species:
66.11
UniProt:
O43861
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43861
NP_940933.3
1147
129304
S453
P
G
T
V
V
R
T
S
T
I
P
E
E
L
G
Chimpanzee
Pan troglodytes
XP_001143568
1108
125190
K430
L
V
Y
L
L
T
D
K
T
G
T
L
T
Q
N
Rhesus Macaque
Macaca mulatta
XP_001087804
1147
129161
S453
P
G
T
V
V
R
T
S
T
I
P
E
E
L
G
Dog
Lupus familis
XP_855968
1147
129093
S452
P
G
T
V
V
R
T
S
T
I
P
E
E
L
G
Cat
Felis silvestris
Mouse
Mus musculus
P98195
1146
128999
S452
P
G
T
V
V
R
T
S
T
I
P
E
E
L
G
Rat
Rattus norvegicus
NP_001099600
1147
129160
S453
P
G
T
V
V
R
T
S
T
I
P
E
E
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509503
1195
134451
S497
P
G
T
V
V
R
T
S
T
I
P
E
E
L
G
Chicken
Gallus gallus
XP_417508
1115
125396
S444
P
G
T
V
V
R
S
S
T
I
P
E
Q
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038619
1108
125101
E428
R
T
S
T
I
P
E
E
L
G
R
L
V
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396589
1276
146194
T584
A
G
T
V
V
R
T
T
T
I
P
E
E
L
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799223
1105
125600
T434
P
G
T
V
V
R
S
T
T
I
P
E
E
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P98205
1107
124818
F430
G
S
T
D
V
I
R
F
L
T
V
M
A
I
C
Baker's Yeast
Sacchar. cerevisiae
P40527
1151
130199
R460
T
I
I
P
V
S
L
R
V
N
L
D
L
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
98.5
92.5
N.A.
93.2
93
N.A.
87.1
70
N.A.
81.7
N.A.
N.A.
55.6
N.A.
60.7
Protein Similarity:
100
96.4
99.3
96.4
N.A.
97
97.1
N.A.
91.8
81.3
N.A.
88.9
N.A.
N.A.
70.9
N.A.
76.8
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
100
86.6
N.A.
0
N.A.
N.A.
86.6
N.A.
86.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
N.A.
N.A.
93.3
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
29
47
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.9
65
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
8
0
0
0
70
62
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
70
0
0
0
0
0
0
0
16
0
0
0
0
70
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
8
0
0
0
70
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% K
% Leu:
8
0
0
8
8
0
8
0
16
0
8
16
8
70
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% N
% Pro:
62
0
0
8
0
8
0
0
0
0
70
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
8
0
0
0
0
70
8
8
0
0
8
0
0
0
0
% R
% Ser:
0
8
8
0
0
8
16
54
0
0
0
0
0
0
0
% S
% Thr:
8
8
77
8
0
8
54
16
77
8
8
0
8
0
0
% T
% Val:
0
8
0
70
85
0
0
0
8
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _